Category Archives: Medical News

Systolic Blood Pressure Intervention Trial (SPRINT) – Discuss your views here

A Randomized Trial of Intensive versus Standard Blood-Pressure Control – The SPRINT Trial

This exciting paper has shaken the entire medical world and prompts the question whether BP targets should be radically changed (from 140 mm Hg to 120 mm Hg systolic*in many patients with increased cardiovascular risk).*

Background

The most appropriate targets for systolic blood pressure to reduce cardiovascular morbidity and mortality among persons without diabetes remain uncertain.

Methods

We randomly assigned 9361 persons with a systolic blood pressure of 130 mm Hg or higher and an increased cardiovascular risk, but without diabetes, to a systolic blood-pressure target of less than 120 mm Hg (intensive treatment) or a target of less than 140 mm Hg (standard treatment). The primary composite outcome was myocardial infarction, other acute coronary syndromes, stroke, heart failure, or death from cardiovascular causes.

Results

At 1 year, the mean systolic blood pressure was 121.4 mm Hg in the intensive-treatment group and 136.2 mm Hg in the standard-treatment group. The intervention was stopped early after a median follow-up of 3.26 years owing to a significantly lower rate of the primary composite outcome in the intensive-treatment group than in the standard-treatment group (1.65% per year vs. 2.19% per year; hazard ratio with intensive treatment, 0.75; 95% confidence interval [CI], 0.64 to 0.89; P<0.001). All-cause mortality was also significantly lower in the intensive-treatment group (hazard ratio, 0.73; 95% CI, 0.60 to 0.90; P=0.003). Rates of serious adverse events of hypotension, syncope, electrolyte abnormalities, and acute kidney injury or failure, but not of injurious falls, were higher in the intensive-treatment group than in the standard-treatment group.

Conclusions

Among patients at high risk for cardiovascular events but without diabetes, targeting a systolic blood pressure of less than 120 mm Hg, as compared with less than 140 mm Hg, resulted in lower rates of fatal and nonfatal major cardiovascular events and death from any cause, although significantly higher rates of some adverse events were observed in the intensive-treatment group. (Funded by the National Institutes of Health; ClinicalTrials.gov number, NCT01206062.)

Posted from WordPress for Android – Google Nexus 5
https://www​.facebook.com/MedicalGeek
https://in.groups.yahoo.com/neo/groups/only4medical/

Nobel Prize in Medicine 2015 awarded jointly to William C Campbell, Satoshi Omura and Youyou Tu

image

The Nobel Prize 2015 in Physiology or Medicine jointly went to William C. Campbell and Satoshi Ōmura, and Youyou Tu.

Mr. Campbell and Mr. Omura won it for “their discoveries concerning a novel therapy against infections caused by roundworm parasites”, while Ms. Tu won it for “her discoveries concerning a novel therapy for malaria.”

Mr. Campbell and Mr. Ōmura discovered a new drug, Avermectin, the derivatives of which have radically lowered the incidence of River Blindness and Lymphatic Filariasis, said a press relase. “The drug also showed efficacy against an expanding number of other parasitic diseases,” it added.

Youyou Tu discovered Artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from Malaria.

“The two discoveries have provided humankind with powerful new means to combat these debilitating diseases that affect hundreds of millions of people annually,” the committee said. “The consequences in terms of improved human health and reduced suffering are immensurable.”

Campbell is a research fellow emeritus at Drew University in Madison, New Jersey. Omura, 80, is a professor emeritus at Kitasato University in Japan and is from the central prefecture of Yamanashi. Tu is chief professor at the China Academy of Traditional Chinese Medicine.

The medicine award was the first Nobel Prize to be announced. The winners of the physics, chemistry and peace prizes are set to be announced later this week. The economics prize will be announced next Monday. No date has been set yet for the literature prize, but it is expected to be announced on Thursday.

The winners will share the 8 million Swedish kronor (about $960,000) prize money with one half going to Campbell and Omura, and the other to Tu. Each winner will also get a diploma and a gold medal at the annual award ceremony on Dec. 10, the anniversary of the death of prize founder Alfred Nobel.

Last year’s medicine award went to three scientists who discovered the brain’s inner navigation system.

Posted from WordPress for Android – Google Nexus 5
https://www​.facebook.com/MedicalGeek
https://in.groups.yahoo.com/neo/groups/only4medical/

Govt won’t issue NORI to doctors to check brain drain: Health Minister JP Nadda

Health Minister J P Nadda today informed Rajya Sabha that the Ministry has revised its guidelines to tackle large scale immigration of Indian doctors to foreign shores.

To tackle brain drain of doctors, the government has decided not to issue ‘No Obligation to Return to India’ certificate to doctors in any circumstances, except to those who are over 65 years of the age.

Health Minister J P Nadda today informed Rajya Sabha that the Ministry has revised its guidelines to tackle large scale immigration of Indian doctors to foreign shores.

“As per the revised guidelines of the Ministry of Health and Family Welfare, ‘No Obligation to Return to India (NORI)’ certificate will not be issued in any circumstance, except for those who are above 65 years of age,” He said.

Nadda was replying to a question whether the country was witnessing a huge brain drain of doctors that directly affect the health sector and whether the government has taken stringent action to stop this.

“During 2010-2014, a total number of 3,947 Statement of Need (SON) Certificates and Exceptional Need Certificates (ENC) were issued by the Health Ministry to Indian doctors to enable them to pursue higher medical studies in the United States of America (USA),” he said.

The government has taken measures to improve the working conditions of the doctors including “considerable” enhancement of pay and allowances of doctors after implementation of the 6th Central Pay Commission, Nadda said.

The other measures include amendment of MCI regulations to provide the age of superannuation for doctors in teaching cadre can go up to 70 years, revision of Assured Career Progression Scheme for faculty of central government institutions to make it more beneficial.

Nadda said that various allowances available to the faculty like Non-Practising Allowance, Conveyance Allowance, Learning Resource Allowance and others have been also been enhanced considerably.

Posted from WordPress for Android – Google Nexus 5
https://www​.facebook.com/MedicalGeek
https://in.groups.yahoo.com/neo/groups/only4medical/

Queensland Safe night out strategy at work for public officers like health workers, nurses, doctors, ambulance officers and police

image

We need similar laws to prevent violence against Doctors & Paramedics.
If Queensland can do it, then why can’t the Indian Government?

http://www.qld.gov.au/law/crime-and-police/crime-prevention-and-statistics/a-safe-night-out-and-banning-notices/a-safe-night-out-at-work/

Queensland Law

Posted from WordPress for Android – Google Nexus 5
https://www​.facebook.com/MedicalGeek
https://in.groups.yahoo.com/neo/groups/only4medical/